IJE TRANSACTIONS B: Applications Vol. 27, No. 8 (August 2014) 1167-1172   

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S. Soleimani, G. Pennati and G. Dubini
( Received: February 21, 2014 – Accepted: April 17, 2014 )

Abstract    In this study the rheology of blood clot is measured with the help of rotational rheometer. Several shear strain (0.5, 1 and 2%) are applied with two frequencies (5 and 10 Hz) from the incipient time of clot formation and the response of the sample is measured with the form of shear stress and the phase lag which is interpreted with storage and loss moduli. In this study the ratio of loss to storage modulus is studied and the blood clot gel-point as the transition from viscoelastic fluid to viscoelastic solid is investigated.


Keywords    Blood clot, loss to storage modulus ratio, gel point


چکیده    در این مطالعه، رئولوژی لخته خو نبا استفاده از دستگاه رئومتر چرخشی اندازه گرفته می شود. تنشهای برشی متعددی (5/0، 1 و 2 درصد) در دو فرکانس (5 و 10 هرتز) از زمان اولیه تشکیل لخته به کار گرفته می شود و پاسخ نمونه به شکل تنش برشی و تاخیر فاز اندازه گیری می گردد که با مدول ذخیره سازی وکاهش تفسیر می شود. در این تحقیق، نسبت مدول کاهش به ذخیره سازی مورد مطالعه قرار گرفته و نقطه-ژل لخته خون به عنوان گذار ازسیال ویسکوالاستیک به جامد ویسکوالاستیک بررسی شده است. با افزایش فرکانس، "دلتا تن" قبل ازنقطه-ژل کاهش و بعد از نقطه-ژل افزایش می یابد که به ترتیب رفتار سیال ویسکوالاستیک و جامد ویسکوالاستیک را نشان می دهد. علاوه بر این،با افزایش تنش برشی، "دلتا تن" با نرخ پایین تری در حالت سیال (Ra1وRa3) وبا نرخ بالاتری در حالت جامد (Ra2 وRa4) تغییر می کند. همچنین نشان داده می شود که افزایش فشار برشی باعث تاخیر در تشکیل نقطه-ژل می گردد.


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